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| April 23, 2018 | 0 Comments

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Figure 2010-2015 global ethionamide manufacturers production share.

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Ethionamide is contraindicated in patients with severe hepatic impairment and should be used with caution in patients with less severe hepatic impairment.

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Comparison of bacteristatic and bactericidal activity of isoniazid and ethionamide against mycobacterium avium and mycobacterium tuberculosis.

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Ethionamide t 2 3 h and prothionamide t 2 3h are bactericidal drugs.

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Metabolism is presumed to occur in the liver and thus far 6 metabolites have been isolated 2-ethylisonicotinamide, carbonyl-dihydropyridine, thiocarbonyl-dihydropyridine, s-oxocarbamoyl dihydropyridine, 2-ethylthioiso-nicotinamide, and ethionamide sulphoxide.

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